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Harmsen Lab

eagle-i ID


Resource Type

  1. Laboratory


  1. Resource Description
    "Research in the Harmsen Lab encompasses the areas of Pulmonary Immunology and Immunopathology. The lung is extremely susceptible to infection because of the constant deposition of potential pathogens in the airways that results from breathing contaminated air. Thus, the lung must respond to these pathogens quickly and intensely to avoid infection. Although these host immune and inflammatory responses usually are successful in preventing infection, these processes can also be damaging to the host. This is especially a problem for the lung because the delicate lace-like structure of lung tissue is easily damaged. In addition, misguided immune responses to inhaled noninfectious antigens, such as allergens, can directly cause serious diseases such as asthma and bronchitis. The major goal of our research is to better understand how the lung immune responses can resist infections and yet limit "collateral" host damage caused by the immune response. In the process of studying these mechanisms of resistance and tissue damage, our lab utilizes animal models of disease. These include mouse models of influenza, Pneumocystis murina pneumonia, Coxiella burnetii, and Streptococcus as well as bovine models of viral and bacterial pneumonia."
  2. PI
    Harmsen, Allen, Ph.D.
  3. Affiliation
    Department of Microbiology and Immunology, Montana State University
  4. Performs Technique
    Cellular assay
  5. Performs Technique
    Pulmonary function tests
  6. Performs Technique
    Bronchoalveolar lavage
  7. Performs Technique
    Multiplexed cytokine assay
  8. Performs Technique
    Histological sample preparation
  9. Performs Technique
    Flow cytometry assay
  10. Website(s)
  11. Website(s)
Provenance Metadata About This Resource Record
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The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016