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Thioredoxin reductase 1 - Conditional Null

eagle-i ID


Resource Type

  1. Mus musculus


  1. Resource Description
    Locus: txnrd1 Allelic designation: txnrd1[cond] Homozygous condition: txnrd1[cond/cond] mRNA designation: Txnrd1 mRNA (also called TrxR1 mRNA, Tr1 mRNA) Protein designation: Txnrd1 (also called TrxR1, Tr1) Origin: Developed on a 129XI ES cell background and backcrossed > 10 generations onto C57Bl/6J. The purely backcrossed line was lost during elimination of MNV from the colony and the line was recovered from individuals that had some ancestors with less defined strain backgrounds (JAX stock #s 007576, 004847, and 003574). These are being continuously backcrossed onto C57Bl/6J. Status: Active. MNV-free. Related disease: Congenital, Hereditary, and Neonatal Diseases and Abnormalities Availability: Heterozygotes of either sex are freely available for unrestricted non-profit research use by qualified programs/institutions. Recipient will pay per diem for production of one liter and will cover costs for health reports and shipping.
  2. Contact
    Schmidt, Ed
  3. Related Disease
  4. Related Publication or Documentation
    Effects of thioredoxin reductase-1 deletion on embryogenesis and transcriptome.
  5. Parental Strain Name
    C57Bl/6J (highly inbred)
  6. Genetic Alteration(s)
  7. Infectious History
    Free from MNV infection.
  8. Location
    Schmidt Lab
Provenance Metadata About This Resource Record
  1. workflow state
  2. contributor
  3. created
  4. creator
    qking (Quinton King)
  5. modified
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The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016