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FPR1 Y301A
eagle-i ID
http://montana.eagle-i.net/i/00000131-0095-e6b5-44b9-3efb80000000
Resource Type
cDNA plasmid
Properties
Construct Insert
FPR1 Y301A
Resource Description
Human FPR1 with Y301A point mutation. Point mutations of human FPR1 cDNA clone R-26 were generated by oligonucleotide-directed mutagenesis and confirmed by DNA sequencing.
Additional Name
fMet-Leu-Phe receptor; Formyl peptide receptor 1
Contact
Miettinen, Heini
Construct Backbone
pBGSA
Accession Number
M60627
Related Publication or Documentation
Identification of putative sites of interaction between the human formyl peptide receptor and G protein.
Related Publication or Documentation
A single amino acid substitution (N297A) in the conserved NPXXY sequence of the human N-formyl peptide receptor results in inhibition of desensitization and endocytosis, and a dose-dependent shift in p42/44 mitogen-activated protein kinase activation and chemotaxis.
Selectable Marker
G418
Related Technique
Transfection
Location
Miettinen Lab
Inferred Types from the eagle-i Ontology (
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entity
continuant
independent_continuant
material_entity
Reagent
Construct
processed material
Plasmid
Thing
Provenance Metadata About This Resource Record
workflow state
Published
contributor
tjohnson
created
2011-07-06T12:55:05.587-05:00
creator
qking (Quinton King)
modified
2016-08-25T15:20:52.059-05:00