CHO-K1 FPR1 Y221A

eagle-i ID

Resource Type

Properties

1. Resource Description

   CHO-K1 cells were transfected with mammalian expression vector pBGSA encoding wild-type and mutant FPR1. Clones were selected in G418 and expression was analyzed by immunofluorescence microscopy.

2. Contact

   Miettinen, Heini

3. Related Publication or Documentation

   Identification of putative sites of interaction between the human formyl peptide receptor and G protein.

4. Related Publication or Documentation

   Activation and nuclear translocation of ERK1/2 by the formyl peptide receptor is regulated by G protein and is not dependent on beta-arrestin translocation or receptor endocytosis.

5. Expressed Construct(s)

   FPR1 Y221A

6. Related Technique

   Immunofluorescence microscopy assay

7. Related Technique

   Transfection

8. Location

   Miettinen Lab