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Hardy Lab

Summary:

Virus-host cell interactions and consequent gene regulation

Current Research

The Hardy laboratory studies interactions between enteric viruses and host cells at the molecular level. We seek to understand how protein-protein interaction networks regulate both viral gene expression and the host cell genetic response to virus invasion. Research in the lab focuses on the rotaviruses, the most important cause of pediatric diarrhea worldwide. Current projects in the lab include molecular and proteomic investigations of how rotaviruses modulate cellular antiviral gene expression, and mechanisms of innate immunity to viral infection.

Affiliations:

People:

Resources:

Organisms and Viruses

Reagents

  • pB-NSP1 ( Expression construct )

    Rotavirus non-structural protein 1 from bovine rotavirus strain B641

  • pN-NSP1 ( Expression construct )

    Rotavirus non-structural protein 1 expression construct derived from the NCDV strain.

  • pO-NSP1 ( Expression construct )

    A non-structural protein 1 (NSP1) expression construct derived from the porcine rotavirus strain OSU.


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Last updated: 2011-04-26T17:24:26.440-05:00

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016