My program is focused on the use of viruses as genetic and molecular tools for fundamental discovery. By combining biochemical and genetic approaches, with the tools of molecular and structural biology. I examine the interplay of viral and host gene products and mechanisms of viral assembly and disassembly. The principle areas of research currently under investigation include:
1. The use of viral protein cages as constrained reaction vessels for nano-materials synthesis with applications in medicine and material sciences.
2. The isolation and genetic characterization of novel viruses from extreme thermal environments found in Yellowstone National Park and other thermal regions worldwide.